Anti-Hepatitis B Virus Surface Antigen ad + ay抗体[HB24] (ab54247)

概述

  • 产品名称Anti-Hepatitis B Virus Surface Antigen ad + ay抗体[HB24]
    参阅全部 Hepatitis B Virus Surface Antigen ad + ay 一抗
  • 描述
    小鼠单克隆抗体[HB24] to乙型肝炎病毒Surface Antigen ad + ay
  • 特异性ab54247 recognises a common epitope of the plasma HBsAg of ad and ay subtypes.
  • 经测试应用适用于: ELISAmore details
  • 种属反应性
    与反应: Hepatitis B virus
  • 免疫原

    Full length native protein (purified) (Hepatitis B virus)

  • 常规说明Affinity 1.4 x 10-9 M (ad) 2.0 x 10-9 M (ay)

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆单克隆
  • 克隆编号HB24
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab54247 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.

靶标

  • 相关性Hepatitis B Virus (HBV) infection induces a disease state characterised by liver damage, inflammation and viral persistence. Infection also increases the risk of hepatocellular carcinoma. HBV belongs to the Hepadnaviridae family of viruses. Its genome consists of partially double stranded circular DNA. The DNA is enclosed in a nucleocapsid, or core antigen (HBcAg), which is surrounded by a spherical envelope (surface antigen or HBsAg). The core antigen shares its sequences with the e antigen (HBeAg) but no cross reactivity between the two proteins has been observed. The HBV genome also encodes a DNA polymerase that also acts as a reverse transcriptase. Hepatitis B infection is normally diagnosed from serological tests that detect HBsAg but as the disease progresses this antigen may no longer be present in the blood and tests for HBcAg are used. If HBsAg can be detected in the blood for longer than six months, chronic hepatitis B is diagnosed. The antigenic determinant of the protein moiety of the HBsAg determines specific characteristics of different serotypes and provides the basis of immunodetection. HBsAg has antigenic heterogeneity, specifically, two pairs of sub specific determinants, d/y and w/r allow the following combinations: adw, ayw, adr, ayr.
  • 细胞定位Secreted
  • 数据库链接
    • 别名
      • HBsAg antibody
      • HBV major surface antigen antibody
      • HBV surface antigen antibody
      • Hepatitis B Virus major surface antigen antibody
      • Major surface antigen antibody
      • S antibody
      see all

    Anti-Hepatitis B Virus Surface Antigen ad + ay antibody [HB24] (ab54247)参考文献

    ab54247 has not yet been referenced specifically in any publications.

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