Anti-Hepatitis B Virus pre S2 Antigen抗体[S9] (ab65406)

概述

  • 产品名称Anti-Hepatitis B Virus pre S2 Antigen抗体[S9]
    参阅全部 Hepatitis B Virus pre S2 Antigen 一抗
  • 描述
    小鼠单克隆抗体[S9] to乙型肝炎病毒pre S2 Antigen
  • 特异性Reacts strongly with WHc but not DHBc in ELISA and Western blot. Also reacts with synthetic HBc peptides.
  • 经测试应用适用于: IHC-P, IHC-Fr, WB, ELISA, ICC/IFmore details
  • 种属反应性
    与反应: Hepatitis B virus
  • 免疫原

    Recombinant full length HBcAg (ayw type)

  • 表位amino acids 130-138 of preS2

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.01% Sodium Azide
    Constituents: 10mM PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆单克隆
  • 克隆编号S9
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab65406 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 31 kDa.
ELISA Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.

靶标

  • 相关性The human hepatitis B virus (HBV) is a DNA virus that causes chronic infections that frequently lead to the development of cirrhosis and cellular hepatocellular carcinoma. The HBsAg (surface antigen) gene is one long open reading frame but contains three in frame "start" (ATG) codons that divide the gene into three sections, pre-S1, pre-S2, and S. Because of the multiple start codons, polypeptides of three different sizes called large, middle, and small (pre-S1 + pre-S2 + S, pre-S2 + S, or S) are produced. The preS2 domain is the minimal functional unit of transcription activators that are encoded by the Hepatitis B virus (HBV) surface (S) gene. It is present in more than one-third of the HBV-integrates in HBV induced hepatocarcinoma (HCC). Pre-S2 is a diagnostically important surface antigen of human hepatitis B virus. The PreS domain (S1 + S2) of Hepatitis B virus (HBV) surface antigen may be a good candidate for an effective vaccine as it activates both B and T cells besides binding to hepatocytes.
  • 细胞定位Virion membrane (By similarity).
  • 数据库链接
    • 别名
      • HBV pre S2 Antigen antibody
      • HBV pre S2 protein antibody
      • Hepatitis B Virus pre S2 protein antibody
      • PreS2/S antigen antibody
      • S antibody
      see all

    Anti-Hepatitis B Virus pre S2 Antigen antibody [S9] (ab65406)参考文献

    ab65406 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for contacting us. The epitope recognized by ab65406 has been mapped to amino acids 130-138 of HBV preS2: MCLRRFIIF. I hope this helps, please let me know if you need any additional information.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"