Anti-Heparin Cofactor II抗体(ab31661)

概述

  • 产品名称
    Anti-Heparin Cofactor II抗体
    参阅全部 Heparin Cofactor II 一抗
  • 描述
    山羊多克隆抗体to Heparin Cofactor II
  • 特异性
    This antibody recognizes Heparin Cofactor II
  • 经测试应用
    适用于: ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Heparin Cofactor II.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液
    Preservative: None
    Constituents: 50% Glycerol, 0.1M Sodium chloride, 0.01M HEPES. pH 6.5
  • Concentration information loading...
  • 纯度
    IgG fraction
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab31661 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.

靶标

  • 功能
    Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner.
    Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.
  • 组织特异性
    Expressed predominantly in liver. Also present in plasma.
  • 疾病相关
    Thrombophilia due to heparin cofactor 2 deficiency
  • 序列相似性
    Belongs to the serpin family.
  • 结构域
    The N-terminal acidic repeat region mediates, in part, the glycosaminoglycan-accelerated thrombin inhibition.
  • 翻译后修饰
    Phosphorylation sites are present in the extracellular medium.
  • Information by UniProt
  • 数据库链接
  • 别名
    • D22S673 antibody
    • HC II antibody
    • HC-II antibody
    • HC2 antibody
    • HCF2 antibody
    • HEP2_HUMAN antibody
    • Heparin cofactor 2 antibody
    • Heparin cofactor II antibody
    • HLS2 antibody
    • Leuserpin 2 antibody
    • LS2 antibody
    • Protease inhibitor leuserpin 2 antibody
    • Protease inhibitor leuserpin-2 antibody
    • serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1 antibody
    • Serpin D1 antibody
    • serpin peptidase inhibitor, clade D (heparin cofactor), member 1 antibody
    • SERPIND1 antibody
    • THPH10 antibody
    see all

文献

ab31661 has not yet been referenced specifically in any publications.

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