产品名称 Anti-HEPACAM抗体 参阅全部 HEPACAM 一抗
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Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
Synthetic peptide corresponding to a region within the N terminal amino acids 107-156 (LLLSDLQLAD EGTYEVEISI TDDTFTGEKT INLTVDVPIS RPQVLVASTT) of Human HEPACAM (NP_689935).
存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
存储溶液 Preservative: None
Constituents: 2% Sucrose, PBS
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纯度 Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 µg/ml. Predicted molecular weight: 46 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
功能 Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation.
序列相似性 Contains 1 Ig-like C2-type (immunoglobulin-like) domain. Contains 1 Ig-like V-type (immunoglobulin-like) domain.
结构域 The cytoplasmic domain plays an important role in regulation of cell-matrix adhesion and cell motility.
细胞定位 Cytoplasm. Membrane. In MCF7 breast carcinoma and hepatic Hep3B and HepG2 cell lines, localization of HEPACAM is cell density-dependent. In well spread cells, localized to punctate structures in the perinuclear membrane, cytoplasm, and at cell surface of protusions. In confluent cells, localized predominantly to the cytoplasmic membrane, particularly in areas of cell-cell contacts. Colocalizes with CDH1.
Information by UniProt
Anti-HEPACAM antibody (ab99122)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"