Selective A2A receptor agonist (Ki = 2.2 nM). Shows good selectivity for A2A over A1 receptors. Displays antiaggregatory activity. Increases cAMP accumulation (EC50 = 43 nM) and inhibits superoxide anion production (EC50 = 3.63 nM) in neutrophils.
Store at +4°C. The product can be stored for up to 12 months.
Soluble in DMSO to 100 mM and in ethanol to 50 mM (with heating)
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.