Anti-Hemoglobin A1c抗体(ab31151)

概述

  • 产品名称Anti-Hemoglobin A1c抗体
    参阅全部 Hemoglobin A1c 一抗
  • 描述
    鸭多克隆抗体to Hemoglobin A1c
  • 特异性This antibody is specific to Hemoglobin A1c.
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Hemoglobin A1c.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.14M Sodium chloride, 10mM PBS, pH 7.2
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purity was determined by SDS PAGE (blue stain), showing that the IgY(delta Fc) constitute was 90% of total protein, and the IgY and IgY (delta Fc) constitute was 95% of total protein.
  • 克隆多克隆
  • 同种型IgY
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab31151 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明ELISA: 1/5000.
    Immunochromatography: Use at an assay dependent dilution.
    Immunoturbidimetry: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 15 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Involved in oxygen transport from the lung to the various peripheral tissues.
      LVV-hemorphin-7 potentiates the activity of bradykinin, causing a decrease in blood pressure.
      Spinorphin: functions as an endogenous inhibitor of enkephalin-degrading enzymes such as DPP3, and as a selective antagonist of the P2RX3 receptor which is involved in pain signaling, these properties implicate it as a regulator of pain and inflammation.
    • 组织特异性Red blood cells.
    • 疾病相关Heinz body anemias
      Beta-thalassemia
      Sickle cell anemia
      Beta-thalassemia, dominant, inclusion body type
    • 序列相似性Belongs to the globin family.
    • 翻译后修饰Glucose reacts non-enzymatically with the N-terminus of the beta chain to form a stable ketoamine linkage. This takes place slowly and continuously throughout the 120-day life span of the red blood cell. The rate of glycation is increased in patients with diabetes mellitus.
      S-nitrosylated; a nitric oxide group is first bound to Fe(2+) and then transferred to Cys-94 to allow capture of O(2).
      Acetylated on Lys-60, Lys-83 and Lys-145 upon aspirin exposure. PubMed:16916647 reports the identification of HBB acetylated on Lys-145 in the cytosolic fraction of HeLa cells. This may have resulted from contamination of the sample.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Beta-globin antibody
      • HBB antibody
      • HBB_HUMAN antibody
      • Hemoglobin beta chain antibody
      • Spinorphin antibody
      see all

    Anti-Hemoglobin A1c antibody (ab31151)参考文献

    ab31151 has not yet been referenced specifically in any publications.

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