概述

  • 产品名称Anti-Hemogen抗体
    参阅全部 Hemogen 一抗
  • 描述
    兔多克隆抗体to Hemogen
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Cat
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 1-50 (MDLGKDQSHL KHHQTPDPHQ EENHSPEVIG TWSLRNRELL RKRKAEVHEK) of Human Hemogen (NM_197978).

  • 阳性对照
    • HT1080 cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Constituents: PBS, 2% Sucrose
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab108430 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 55 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Regulates the proliferation and differentiation of hematopoietic cells. Overexpression block the TPA-induced megakaryocytic differentiation in the K562 cell model. May also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).
  • 组织特异性Expressed in hematopoietic precursor cells (at protein level). Detected in CD34+ and K562 leukemia cell line (at protein level). Expressed in bone marrow, testis, thymus. Also expressed in thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia.
  • 发展阶段Expressed in fetal liver, kidney and brain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EDAG antibody
    • EDAG-1 antibody
    • Erythroid differentiation-associated gene protein antibody
    • Hemgn antibody
    • HEMGN_HUMAN antibody
    • Hemogen antibody
    • Hemopoietic gene protein antibody
    • Negative differentiation regulator protein antibody
    see all

Anti-Hemogen antibody 图像

  • Anti-Hemogen antibody (ab108430) at 1 µg/ml + HT10180 cell lysate at 10 µg

    Predicted band size : 55 kDa

Anti-Hemogen antibody (ab108430)参考文献

ab108430 has not yet been referenced specifically in any publications.

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