Anti-Hemagglutinin抗体[16B12] (DyLight® 488) (ab117488)

概述

  • 产品名称Anti-Hemagglutinin抗体[16B12] (DyLight® 488)
    参阅全部 Hemagglutinin 一抗
  • 描述
    小鼠单克隆抗体[16B12] to Hemagglutinin (DyLight® 488)
  • 偶联物DyLight® 488. Ex: 493nm, Em: 518nm
  • 经测试应用适用于: ICC/IF, Flow Cytmore details
  • 免疫原

    The influenza hemagglutinin epitope (YPYDVPDYA).

性能

应用

Our Abpromise guarantee covers the use of ab117488 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF 1/500 - 1/5000.
Flow Cyt Use at an assay dependent concentration.

靶标

  • 相关性Hemagglutinin (HA) is a class I viral fusion protein from Influenza virus. It is a major glycoprotein, comprising over 80% of the envelope proteins present in the virus particle. HA binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell, and is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. The extent of infection into host organism is determined by HA. In natural infection, inactive HA is matured into HA1 and HA2 outside the cell by one or more trypsin-like, arginine-specific endoproteases secreted by the bronchial epithelial cells. The HA protein is a homotrimer of disulfide-linked HA1-HA2. It also plays a major role in the determination of host range restriction and virulence. Genetic variation of hemagglutinin and/or neuraminidase genes results in the emergence of new influenza strains.
  • 细胞定位Cell membrane; apical cell membrane; single-pass type I membrane protein.
  • 别名
    • HA antibody
    • HA1 antibody
    • HA2 antibody
    • Hemagglutinin antibody

Anti-Hemagglutinin antibody [16B12] (DyLight® 488) 图像

  • ab117488 staining Hemagglutinin in Monkey cos7 cells by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with formaldehyde. Samples were incubated with primary antibody (1/100) for 1 hour at 22°C.

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Anti-Hemagglutinin antibody [16B12] (DyLight® 488) (ab117488)参考文献

ab117488 has not yet been referenced specifically in any publications.

Product Wall

Application Immunocytochemistry/ Immunofluorescence
Sample Monkey Cell (cos7)
Specification cos7
Permeabilization No
Fixative Formaldehyde
Username

Ms. YA ZHOU

Verified customer

提交于 Dec 13 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"