Anti-Helicobacter pylori CagA抗体[B818M] (ab90490)

概述

  • 产品名称Anti-Helicobacter pylori CagA抗体[B818M]
  • 描述
    小鼠单克隆抗体[B818M] to Helicobacter pylori CagA
  • 经测试应用适用于: WB, ELISA, Sandwich ELISAmore details
  • 种属反应性
    Reacts with
  • 免疫原

    Recombinant fragments of CA gene of Helicobacter pylori.

  • 表位ab90490 recognizes an epitope localized between Asp562 and Gln795 in the GenBank FJ428215 amino acid sequence.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein G purified
  • 纯化说明ab90490 is purified from ascites by Protein G chromatography and is >95% pure as assessed by SDS-PAGE.
  • 克隆单克隆
  • 克隆编号B818M
  • 骨髓瘤Sp2/0
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab90490 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 124 kDa.
ELISA Use at an assay dependent concentration.
Sandwich ELISA Use at an assay dependent concentration. This antibody has been tested as the capture antibody, while the recommended pair was used as detection antibody.

靶标

  • 相关性It is known that H. pylori strains exhibit a significant degree of diversity. The great variability in the H. pylori genome may explain why not all infected individuals suffer from ulcer. Some H. pylori strains contain particular pathogenic genes such as cytokine associated gene A (CagA), while others lack these genes. The CagA protein of H. pylori has been found to be associated with more severe clinical manifestations, such as ulcer disease and gastric cancer. Thus, discrimination between potentially virulent strains may be relevant.
  • 别名
    • 120 kDa protein antibody
    • CAG pathogenicity island protein 26 antibody
    • cag26 antibody
    • cagA antibody
    • cai antibody
    • Cytotoxicity-associated immunodominant antigen antibody
    • H. pylori CagA antibody
    • H. pylori cytokine associated gene A antibody
    • Helicobacter pylori cytokine associated gene A antibody
    see all

Anti-Helicobacter pylori CagA antibody [B818M] (ab90490)参考文献

This product has been referenced in:
  • McCracken KW  et al. Modelling human development and disease in pluripotent stem-cell-derived gastric organoids. Nature 516:400-4 (2014). Read more (PubMed: 25363776) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab90490.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"