Anti-Helicobacter pylori抗体(ab20459)

概述

  • 产品名称Anti-Helicobacter pylori抗体
    参阅全部 Helicobacter pylori 一抗
  • 描述
    兔多克隆抗体to Helicobacter pylori
  • 特异性Whole cell lysate. Has not been absorbed and may react with related microorganisms.
  • 经测试应用适用于: ELISA, ICC/IF, Conjugation, IHC-Pmore details
  • 种属反应性
    Reacts with Helicobacter pylori. Not yet tested in other species.
  • 免疫原

    ATCC strain 43504

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: 0.01M PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein A purified
  • 纯化说明>95% pure
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab20459 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/5000.
ICC/IF 1/1000.
Conjugation Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.

靶标

  • 相关性The spiral shaped bacterium Helicobacter pylori is strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy. H. pylori is known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcimona and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach. More recently this bacterium has also been implicated with a number of vascular disorders including heart disease. It is not clear how H. pylori is transmitted or why some patients become symptomatic while others do not. The bacteria are most likely spread from person to person through fecal-to-oral or oral-to-oral routes. Possible environmental reservoirs include contaminated water sources. Serological tests that measure specific H. pylori IgG antibodies can determine if a person has been infected although these methods do have drawbacks and limitations.
  • 别名
    • H. pylori antibody

Anti-Helicobacter pylori antibody (ab20459)参考文献

This product has been referenced in:
  • Hoppe S  et al. Rapid identification of novel immunodominant proteins and characterization of a specific linear epitope of Campylobacter jejuni. PLoS One 8:e65837 (2013). Read more (PubMed: 23734261) »
  • Rossez Y  et al. Almost all human gastric mucin O-glycans harbor blood group A, B or H antigens and are potential binding sites for Helicobacter pylori. Glycobiology 22:1193-206 (2012). Read more (PubMed: 22522599) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"