概述

  • 产品名称
    Anti-HDAC10抗体[EPR3576]
    参阅全部 HDAC10 一抗
  • 描述
    兔单克隆抗体[EPR3576] to HDAC10
  • 经测试应用
    适用于: WB, IP, ICCmore details
    不适用于: Flow Cyt or IHC-P
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    A synthetic peptide corresponding to residues in Human HDAC10

  • 阳性对照
    • HeLa, 293T, Jurkat, HepG2, A673 and NIH/3T3 cell lysates
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

性能

应用

Our Abpromise guarantee covers the use of ab108934 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 75 kDa.
IP 1/10 - 1/100.
ICC 1/100 - 1/250.
  • 应用说明
    Is unsuitable for Flow Cyt or IHC-P.
  • 靶标

    • 功能
      Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    • 组织特异性
      Ubiquitous. High expression in liver, spleen, pancreas and kidney.
    • 序列相似性
      Belongs to the histone deacetylase family. HD type 2 subfamily.
    • 细胞定位
      Cytoplasm. Nucleus. Excluded from the nucleoli.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DKFZP761B039 antibody
      • HD 10 antibody
      • HD10 antibody
      • HDA10_HUMAN antibody
      • HDAC 10 antibody
      • Hdac10 antibody
      • Histone deacetylase 10 antibody
      • MGC149722 antibody
      • OTTHUMP00000028555 antibody
      see all

    图片

    • All lanes : Anti-HDAC10 antibody [EPR3576] (ab108934) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : 293T cell lysate
      Lane 3 : Jurkat cell lysate
      Lane 4 : HepG2 cell lysate
      Lane 5 : A673 cell lysate
      Lane 6 : NIH/3T3 cell lysate

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 75 kDa

    文献

    This product has been referenced in:
    • Mondello P  et al. Panobinostat acts synergistically with ibrutinib in diffuse large B cell lymphoma cells with MyD88 L265 mutations. JCI Insight 2:e90196 (2017). WB ; Human . Read more (PubMed: 28352655) »

    See 1 Publication for this product

    客户评价及客户问答

    There are currently no Customer reviews or Questions for ab108934.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

    注册