Anti-HDAC10抗体- Aminoterminal end (ab71215)

概述

  • 产品名称Anti-HDAC10抗体- Aminoterminal end
    参阅全部 HDAC10 一抗
  • 描述
    兔多克隆抗体to HDAC10 - Aminoterminal end
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    A KLH conjugated synthetic peptide selected from a region of human HDAC10 within amino acids 1-100.

  • 阳性对照
    • A375 cell line lysate and 293 cell lysate transiently transfected with the HDAC10 gene.

性能

应用

Our Abpromise guarantee covers the use of ab71215 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/50 - 1/100. Detects a band of approximately 71 kDa (predicted molecular weight: 71 kDa).

靶标

  • 功能Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
  • 组织特异性Ubiquitous. High expression in liver, spleen, pancreas and kidney.
  • 序列相似性Belongs to the histone deacetylase family. HD type 2 subfamily.
  • 细胞定位Cytoplasm. Nucleus. Excluded from the nucleoli.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZP761B039 antibody
    • HD 10 antibody
    • HD10 antibody
    • HDA10_HUMAN antibody
    • HDAC 10 antibody
    • Hdac10 antibody
    • Histone deacetylase 10 antibody
    • MGC149722 antibody
    • OTTHUMP00000028555 antibody
    see all

Anti-HDAC10 antibody - Aminoterminal end 图像

  • Anti-HDAC10 antibody - Aminoterminal end (ab71215) at 1/100 dilution + A375 cell line lysates at 12.5 µg

    Predicted band size : 71 kDa
    Observed band size : 71 kDa
    Additional bands at : 150 kDa,90 kDa. We are unsure as to the identity of these extra bands.
  • All lanes : Anti-HDAC10 antibody - Aminoterminal end (ab71215) at 1/100 dilution

    Lane 1 : 293 cell lysates non transfected
    Lane 2 : 293 cell lysates transiently transfected with the HDAC10 gene

    Lysates/proteins at 2 µg per lane.


    Predicted band size : 71 kDa
    Observed band size : 71 kDa
    Additional bands at : 50 kDa. We are unsure as to the identity of these extra bands.

Anti-HDAC10 antibody - Aminoterminal end (ab71215)参考文献

ab71215 has not yet been referenced specifically in any publications.

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