概述

  • 产品名称Anti-HDAC10抗体
    参阅全部 HDAC10 一抗
  • 描述
    兔多克隆抗体to HDAC10
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide, corresponding to amino acids near the N terminus of Human HDAC10.

  • 阳性对照
    • Jurkat Cells, Mouse Intestine and Rat Brain for Western blot.

性能

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应用

Our Abpromise guarantee covers the use of ab18971 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1 - 4 µg/ml. Detects a band of approximately 74 kDa (predicted molecular weight: 71 kDa). A 55 kDa band can also be detected in mouse and rat tissue lysate.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    • 组织特异性Ubiquitous. High expression in liver, spleen, pancreas and kidney.
    • 序列相似性Belongs to the histone deacetylase family. HD type 2 subfamily.
    • 细胞定位Cytoplasm. Nucleus. Excluded from the nucleoli.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DKFZP761B039 antibody
      • HD 10 antibody
      • HD10 antibody
      • HDA10_HUMAN antibody
      • HDAC 10 antibody
      • Hdac10 antibody
      • Histone deacetylase 10 antibody
      • MGC149722 antibody
      • OTTHUMP00000028555 antibody
      see all

    Anti-HDAC10 antibody 图像

    • All lanes : Anti-HDAC10 antibody (ab18971) at 2.5 µg/ml

      Lane 1 : Jurkat cell lysate (30ug)
      Lane 2 : Mouse intestine lysate (30ug)
      Lane 3 : Rat brain lysate (30ug)


      Predicted band size : 71 kDa
      Observed band size : 74 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 55 kDa. We are unsure as to the identity of these extra bands.

    Anti-HDAC10 antibody (ab18971)参考文献

    This product has been referenced in:
    • Liu J  et al. Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells. J Transl Med 14:7 (2016). Human . Read more (PubMed: 26747087) »

    See 1 Publication for this product

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