概述

  • 产品名称
  • 描述
    山羊多克隆抗体to HCN3
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Rat
    预测可用于: Cow, Human
  • 免疫原

    Synthetic peptide:

    C-RGVRGRAPSTGAQ

    , corresponding to internal sequence amino acids 583-595 of Human HCN3 (NP_065948.1).

  • 阳性对照
    • Rat kidney lysate

性能

应用

Our Abpromise guarantee covers the use of ab109807 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 85 kDa (predicted molecular weight: 86 kDa).

靶标

  • 功能
    Putative hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions.
  • 序列相似性
    Belongs to the potassium channel HCN family.
    Contains 1 cyclic nucleotide-binding domain.
  • 结构域
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Hcn3 antibody
    • HCN3_HUMAN antibody
    • hyperpolarization activated cyclic nucleotide-gated potassium channel 3 antibody
    • KIAA1535 antibody
    • Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 antibody
    see all

图片

  • Anti-HCN3 antibody (ab109807) at 1 µg/ml + Rat kidney lysate (in RIPA buffer) at 35 µg
    Developed using the ECL technique

    Predicted band size : 86 kDa
    Observed band size : 85 kDa (why is the actual band size different from the predicted?)


    Exposure time : 1 hour

实验方案

文献

This product has been referenced in:
  • Kretschmannova K  et al. The expression and role of hyperpolarization-activated and cyclic nucleotide-gated channels in endocrine anterior pituitary cells. Mol Endocrinol 26:153-64 (2012). WB ; Rat . Read more (PubMed: 22135067) »

See 1 Publication for this product

客户评价及客户问答

There are currently no Customer reviews or Questions for ab109807.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册