, corresponding to internal sequence amino acids 583-595 of Human HCN3 (NP_065948.1).
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
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Immunogen affinity purified
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 85 kDa (predicted molecular weight: 86 kDa).
Putative hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions.
Belongs to the potassium channel HCN family.
Contains 1 cyclic nucleotide-binding domain.
The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
Information by UniProt
hyperpolarization activated cyclic nucleotide-gated potassium channel 3 antibody
Anti-HCN3 antibody 图像
Western blot - HCN3 antibody (ab109807)
Anti-HCN3 antibody (ab109807)参考文献
This product has been referenced in:
et al. The expression and role of hyperpolarization-activated and cyclic nucleotide-gated channels in endocrine anterior pituitary cells. Mol Endocrinol 26:153-64 (2012).
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