Anti-HCLS1抗体(ab56039)

概述

  • 产品名称Anti-HCLS1抗体
    参阅全部 HCLS1 一抗
  • 描述
    兔多克隆抗体to HCLS1
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Mouse, Rat, Human
  • 免疫原

    A synthetic peptide corresponding to N-terminal residues of human HCLS1

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.01% Sodium Azide
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab56039 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 54 kDa. for 2 hours. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression.
  • 组织特异性Expressed only in tissues and cells of hematopoietic origin.
  • 序列相似性Contains 4 cortactin repeats.
    Contains 1 SH3 domain.
  • 发展阶段Expressed in early stage of myeloid and erythroid differentiation.
  • 翻译后修饰Phosphorylated by LYN; rapidly after cross-linking of surface IgM on B-cells.
  • 细胞定位Membrane. Cytoplasm. Mitochondrion.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cortactin like antibody
    • CTTNL antibody
    • HCLS 1 antibody
    • Hcls1 antibody
    • HCLS1_HUMAN antibody
    • Hematopoietic cell specific Lyn substrate 1 antibody
    • Hematopoietic cell-specific LYN substrate 1 antibody
    • Hematopoietic lineage cell-specific protein antibody
    • HS 1 antibody
    • HS1 antibody
    • LckBP1 antibody
    • OTTHUMP00000215180 antibody
    • OTTHUMP00000215182 antibody
    • p75 antibody
    see all

Anti-HCLS1 antibody (ab56039)参考文献

ab56039 has not yet been referenced specifically in any publications.

Product Wall

The alignment results suggest that ab56039, anti-HCLS1, is in fact likely to cross-react with cortactin. The immunogen is 88% identical to human cortactin (UniProt Q14247). Thank you for alerting us to this possibility.

Thank you for contacting us. The two antibodies that appear to have the least likelihood of cross-reacting with human cortactin are the mouse monoclonal ab55090 and the rabbit polyclonal ab116521.

There was no significant homology between an...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"