概述

  • 产品名称Anti-HBXIP抗体
    参阅全部 HBXIP 一抗
  • 描述
    兔多克隆抗体to HBXIP
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 43-92 (FVPLEAPLRS TPRSRQVTEA CGGEGRAVPL GSEPEWSVGG MEATLEQHLE) of Human HBXIP (NP_006393).

  • 阳性对照
    • COLO205 cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab125410 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 10 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication.
  • 组织特异性Highly expressed in skeletal and cardiac muscle, followed by pancreas, kidney, liver, brain, placenta and lung. Elevated levels in both cancerous and non-cancerous liver tissue of patients with chronic HBV infection compared with hepatic tissue without HBV infection.
  • 序列相似性Belongs to the HBXIP family.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • HBV X interacting protein antibody
    • HBV X-interacting protein antibody
    • HBX interacting protein antibody
    • HBX-interacting protein antibody
    • hbxip antibody
    • HBXIP_HUMAN antibody
    • Hepatitis B virus X interacting protein antibody
    • Hepatitis B virus X-interacting protein antibody
    • LAMTOR5 antibody
    • Late endosomal/lysosomal adaptor MAPK and MTOR activator 5 antibody
    • MGC71071 antibody
    • Ragulator complex protein LAMTOR5 antibody
    • XIP antibody
    see all

Anti-HBXIP antibody 图像

  • Anti-HBXIP antibody (ab125410) at 1 µg/ml + COLO205 cell lysate at 10 µg

    Predicted band size : 10 kDa

Anti-HBXIP antibody (ab125410)参考文献

ab125410 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab125410.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"