Anti-HB9/HLXB9/MNX1抗体(ab92606)
Key features and details
- Rabbit polyclonal to HB9/HLXB9/MNX1
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-HB9/HLXB9/MNX1抗体
参阅全部 HB9/HLXB9/MNX1 一抗 -
描述
兔多克隆抗体to HB9/HLXB9/MNX1 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Mouse, Human
预测可用于: Dog -
免疫原
Synthetic peptide corresponding to Mouse HB9/HLXB9/MNX1 aa 330-380.
Database link: NP_064328.2 -
阳性对照
- WB: MOLT 4 cell lysate; IHC-P: Mouse pancreas tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.05% BSA -
Concentration information loading...
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纯度
Protein A purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab92606于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 41 kDa.
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IHC-P |
Use a concentration of 5 µg/ml.
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说明 |
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WB
Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 41 kDa. |
IHC-P
Use a concentration of 5 µg/ml. |
靶标
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功能
Putative transcription factor involved in pancreas development and function. -
组织特异性
Expressed in lymphoid and pancreatic tissues. -
疾病相关
Defects in MNX1 are a cause of Currarino syndrome (CURRAS) [MIM:176450]. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait. -
序列相似性
Contains 1 homeobox DNA-binding domain. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 3110 Human
- Entrez Gene: 15285 Mouse
- Omim: 142994 Human
- SwissProt: P50219 Human
- SwissProt: Q9QZW9 Mouse
- Unigene: 37035 Human
- Unigene: 103760 Mouse
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别名
- HB 9 antibody
- HB9 antibody
- HLXB 9 antibody
see all
图片
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Immunohistochemistry analysis of HB9/HLXB9/MNX1 expression in formalin-fixed, paraffin-embedded Mouse pancreas tissue using: an isotype control (1) or ab92606 at 5µg/ml (2 and 3).
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All lanes : Anti-HB9/HLXB9/MNX1 antibody (ab92606) at 0.5 µg/ml
Lane 1 : MOLT 4 cell lysate
Lane 2 : MOLT 4 cell lysate with immunizing peptide
Secondary
All lanes : HRP-conjugated Goat anti-Rabbit IgG
Predicted band size: 41 kDa
数据表及文件
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SDS download
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Datasheet download
文献 (6)
ab92606 被引用在 6 文献中.
- Miralles MP et al. Survival motor neuron protein and neurite degeneration are regulated by Gemin3 in spinal muscular atrophy motoneurons. Front Cell Neurosci 16:1054270 (2022). PubMed: 36619669
- Sansa A et al. Intracellular pathways involved in cell survival are deregulated in mouse and human spinal muscular atrophy motoneurons. Neurobiol Dis 155:105366 (2021). PubMed: 33845129
- Sansa A et al. Spinal Muscular Atrophy autophagy profile is tissue-dependent: differential regulation between muscle and motoneurons. Acta Neuropathol Commun 9:122 (2021). PubMed: 34217376
- de la Fuente S et al. Calpain system is altered in survival motor neuron-reduced cells from in vitro and in vivo spinal muscular atrophy models. Cell Death Dis 11:487 (2020). PubMed: 32587237
- Cosset É et al. Modeling Poliovirus Infection Using Human Engineered Neural Tissue Enriched With Motor Neuron Derived From Embryonic Stem Cells. Front Cell Dev Biol 8:593106 (2020). PubMed: 33490061
- Osaki T et al. On-chip 3D neuromuscular model for drug screening and precision medicine in neuromuscular disease. Nat Protoc 15:421-449 (2020). PubMed: 31932771