概述

  • 产品名称Anti-HB9/HLXB9抗体
    参阅全部 HB9/HLXB9 一抗
  • 描述
    羊多克隆抗体to HB9/HLXB9
  • 特异性The antibody is specific for HB9 in Human and Mouse. This has been confirmed by Immunohistochemical analysis of Normal Term and First Trimester Human Placenta as well as western blot analysis of mouse Neuroblastoma and Spinal Cord cells (NSC-34).
  • 经测试应用适用于: IHC-P, ELISA, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide: H-

    APADRLRAESPSPPRLLAAHC

    -NH2 conjugated to Blue Carrier Protein, corresponding to amino acids 68-88 of Human HB9/HLXB9

  • 阳性对照
    • Normal Term and First Trimester Human Placenta and Mouse Neuroblastoma and Spinal Cord cells (NSC-34).

性能

应用

Our Abpromise guarantee covers the use of ab64058 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent dilution.
ELISA 1/200 - 1/2600.
WB 1/400. Predicted molecular weight: 41 kDa.

靶标

  • 功能Putative transcription factor involved in pancreas development and function.
  • 组织特异性Expressed in lymphoid and pancreatic tissues.
  • 疾病相关Defects in MNX1 are a cause of Currarino syndrome (CURRAS) [MIM:176450]. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait.
  • 序列相似性Contains 1 homeobox DNA-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • HB 9 antibody
    • HB9 antibody
    • HLXB 9 antibody
    • HLXB9 antibody
    • Homeo box HB9 antibody
    • Homeobox HB9 antibody
    • Homeobox protein HB9 antibody
    • HOXHB9 antibody
    • MNX1 antibody
    • MNX1_HUMAN antibody
    • Motor neuron and pancreas homeobox protein 1 antibody
    • Sacral agenesis autosomal dominant (Currarino triad) antibody
    • SCRA 1 antibody
    • SCRA1 antibody
    see all

Anti-HB9/HLXB9 antibody (ab64058)参考文献

This product has been referenced in:

See 1 Publication for this product

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Mouse Tissue sections (Spinal cord at embryonic day e12.5)
Specification Spinal cord at embryonic day e12.5
Fixative Paraformaldehyde
Permeabilization No
Blocking step Serum as blocking agent for 30 minute(s) · Concentration: 10% · Temperature: 20°C
Username

Dr. Frederic Clotman

Verified customer

提交于 Apr 20 2010

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"