特异性This antibody reacts with nucleocapsid proteins of Puumala hantaviruses: Vranica, Sotkamo and Kazan and reacts with hantavirus-infected cells. It cross-reacts with nucleocapsid proteins of Andes, Sin Nombre and Seoul hantaviruses.
It does not cross-react with hamster polyomavirus major capsid protein VP1, nor with nucleocapsid proteins of measles and mumps viruses.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用说明IF: Neat - 1/20.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
相关性The members of the Hantavirus genus of the family Bunyaviridae are spherical, enveloped viruses containing tripartite negative-sense RNA as their genome. The three genomic RNA segments, designated L, M, and S, encode an RNA-dependent RNA polymerase, envelope glycoproteins (G1 and G2), and nucleocapsid (N) protein, respectively. Hantavirus infections can cause two serious and often fatal human diseases, hemorrhagic fever with renal syndrome and hantaviral pulmonary syndrome, characterized by lung damage and cardiac dysfunction. Humans are infected with hantaviruses from rodent reservoirs that are persistently infected without signs of disease.
Anti-Hantavirus nucleocapsid protein antibody (ab34759)参考文献
This product has been referenced in:
Perelygina L et al. Persistent infection of human fetal endothelial cells with rubella virus. PLoS One8:e73014 (2013).
Read more (PubMed: 23940821) »