Anti-Hantavirus nucleocapsid protein抗体[5E11] (ab34757)

概述

  • 产品名称
    Anti-Hantavirus nucleocapsid protein抗体[5E11]
  • 描述
    小鼠单克隆抗体[5E11] to Hantavirus nucleocapsid protein
  • 特异性
    Does not cross-react with nucleocapsid proteins of measles and mumps viruses.
  • 经测试应用
    适用于: Indirect ELISA, WB, ICC/IFmore details
  • 种属反应性
    Reacts with nucleocapsid proteins of Puumala hantaviruses: Vranica, Sotkamo and Kazan and reacts with hantavirus-infected cells. It reacts with nucleocapsid proteins of Andes, Sin Nombre and Seoul hantaviruses. It does not cross-react with hamster polyomavirus major capsid protein VP1 Not yet tested in other species.
  • 免疫原

    Recombinant fragment corresponding to Hantavirus nucleocapsid protein.

  • 表位
    The epitope recognized by this antibody is localized at N-terminus, between amino acids 1 and 45 of the hantavirus nucleocapsid protein.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度
    IgG fraction
  • 克隆
    单克隆
  • 克隆编号
    5E11
  • 骨髓瘤
    Sp2/0
  • 同种型
    IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab34757 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Indirect ELISA 1/1000 - 1/10000.
WB 1/1000 - 1/5000.
ICC/IF Use at an assay dependent dilution. PubMed: 18687679

靶标

  • 相关性
    The members of the Hantavirus genus of the family Bunyaviridae are spherical, enveloped viruses containing tripartite negative-sense RNA as their genome. The three genomic RNA segments, designated L, M, and S, encode an RNA-dependent RNA polymerase, envelope glycoproteins (G1 and G2), and nucleocapsid (N) protein, respectively. Hantavirus infections can cause two serious and often fatal human diseases, hemorrhagic fever with renal syndrome and hantaviral pulmonary syndrome, characterized by lung damage and cardiac dysfunction. Humans are infected with hantaviruses from rodent reservoirs that are persistently infected without signs of disease.

Anti-Hantavirus nucleocapsid protein antibody [5E11] 图像

  • ab34757 at 1 µg/mL used in Western blot of recombinant nucleocapsid proteins.

    Lane 1 Sotkamo NP

    Lanes 2 & 3 Vranica NP

    Lane 4 Kazan NP

Anti-Hantavirus nucleocapsid protein antibody [5E11] (ab34757)参考文献

This product has been referenced in:
  • Wang Y  et al. NMR structure of the N-terminal coiled coil domain of the Andes hantavirus nucleocapsid protein. J Biol Chem 283:28297-304 (2008). ICC/IF . Read more (PubMed: 18687679) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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