Anti-HAND2抗体- Carboxyterminal end (ab60037)

概述

  • 产品名称Anti-HAND2抗体- Carboxyterminal end
    参阅全部 HAND2 一抗
  • 描述
    兔多克隆抗体to HAND2 - Carboxyterminal end
  • 经测试应用适用于: ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (10-30 aa in length) at the C-terminal of last 50 aa of human HAND2 conjugated to KLH

  • 阳性对照
    • Human hepatocarcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab60037 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
IHC-P 1/50 - 1/100.

靶标

  • 功能Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'.
  • 组织特异性Heart.
  • 序列相似性Contains 1 basic helix-loop-helix (bHLH) domain.
  • 发展阶段Expressed in the fetal heart.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI225906 antibody
    • AI661148 antibody
    • autonomic nervous system and neural crest derivatives-expressed protein 2 antibody
    • Basic helix loop helix transcription factor HAND2 antibody
    • bHLHa26 antibody
    • Class A basic helix-loop-helix protein 26 antibody
    • Deciduum antibody
    • Deciduum heart autonomic nervous system and neural crest derivatives expressed protein 2 antibody
    • DHAND 2 antibody
    • dHAND antibody
    • DHAND2 antibody
    • Ehand 2 antibody
    • Ehand2 antibody
    • FLJ16260 antibody
    • HAND 2 antibody
    • Hand2 antibody
    • HAND2_HUMAN antibody
    • Heart and neural crest derivatives expressed 2 antibody
    • Heart and neural crest derivatives expressed protein 2 antibody
    • heart and neural crest derivatives expressed transcript 2 antibody
    • heart antibody
    • Heart- and neural crest derivatives-expressed protein 2 antibody
    • Hed antibody
    • Highly similar to dHAND M musculus antibody
    • MGC125303 antibody
    • MGC125304 antibody
    • Th 2 antibody
    • Th2 antibody
    • Thing 2 antibody
    • Thing2 antibody
    see all

Anti-HAND2 antibody - Carboxyterminal end 图像

  • ab60037 at 1/50 dilution staining HAND2 in Human hepatocarcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. A peroxidase-conjugated secondary antibody was used, followed by AEC staining.

Anti-HAND2 antibody - Carboxyterminal end (ab60037)参考文献

ab60037 has not yet been referenced specifically in any publications.

Product Wall

Thank you for calling us and for alerting us to the problem you are experiencing with the anti-HAND2 antibody (ab60037). We take product complaints very seriously, and investigate every product that we feel may not be performing correctly.

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Thank you for contacting us.

We have 3 antibodies available in Abcam catalogue; the numbers are ab10131, ab56590 and ab60037. Please choose any one of these for testing.

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Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Dogfish/Catshark Tissue sections (Stage 28 embryos. Level of posterior pectoral fin)
Specification Stage 28 embryos. Level of posterior pectoral fin
Fixative Paraformaldehyde
Permeabilization No
Blocking step Serum as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 20°C
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Abcam user community

Verified customer

提交于 Nov 10 2011

Thank you for getting back to me and for providing some further information. To our knowledge, ab60037 has not been tested in catshark - only in human. The immunogenic sequence of ab60037 shares 93% homology with catshark and it is very surprisi...

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Thank you for contacting Abcam Technical Team and for taking the time to provide some useful details of the experiments. I am very sorry to hear that you are having problems with our product. This antibody has only been tested in human only and ...

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Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Mouse Tissue sections (Cartilage)
Specification Cartilage
Fixative Paraformaldehyde
Permeabilization Yes - 0.1% Triton
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 20% · Temperature: 19°C
Username

Abcam user community

Verified customer

提交于 Jan 21 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"