概述

  • 产品名称Anti-HABP2抗体
    参阅全部 HABP2 一抗
  • 描述
    小鼠单克隆抗体to HABP2
  • 经测试应用适用于: ELISAmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant fragment: GNKCQKVQNT CKDNPCGRGQ CLITQSPPYY RCVCKHPYTG PSCSQVVPVC RPNPCQNGAT CSRHKRRSKF TCACPDQFKG KFCEIGSDDC YVGDGYSYRG , corresponding to amino acids 105-205 of Human HABP2

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab55229 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.

靶标

  • 功能Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII.
  • 组织特异性Ubiquitously expressed.
  • 序列相似性Belongs to the peptidase S1 family.
    Contains 3 EGF-like domains.
    Contains 1 kringle domain.
    Contains 1 peptidase S1 domain.
  • 翻译后修饰Proteolytic cleavage at Gly-23 or Met-27 can give rise to the 50 kDa heavy chain and cleavage at Arg-313 or Lys-319 can give rise to the 27 kDa light chain. The heavy chain can undergo further proteolytic cleavage at Lys-169 or Arg-170 to give rise to 2 inactive 26 kDa fragments and the light chain can undergo further proteolytic cleavage at Arg-480 to give rise to inactive 17 kDa and 8 kDa fragments.
  • 细胞定位Secreted. Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Factor seven activating protease antibody
    • Factor seven-activating protease antibody
    • Factor VII activating protein antibody
    • Factor VII-activating protease antibody
    • FSAP antibody
    • HABP 2 antibody
    • HABP antibody
    • Habp2 antibody
    • HABP2_HUMAN antibody
    • Hepatocyte growth factor activator like protein antibody
    • Hepatocyte growth factor activator-like protein antibody
    • HGFAL antibody
    • Hyaluronan binding protein 2 antibody
    • Hyaluronan-binding protein 2 27 kDa light chain alternate form antibody
    • Hyaluronic acid binding protein 2 antibody
    • PHBP antibody
    • Plasma hyaluronan binding protein antibody
    • Plasma hyaluronan-binding protein antibody
    see all

Anti-HABP2 antibody 图像

  • ab55229, staining HABP2 by Elisa. The detection limit for recombinant tagged HABP2 is approximately 1ng/ml as a capture antibody.

Anti-HABP2 antibody (ab55229)参考文献

ab55229 has not yet been referenced specifically in any publications.

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