Anti-H3 (H3N2)抗体[InA227] (ab82454)

概述

  • 产品名称
    Anti-H3 (H3N2)抗体[InA227]
  • 描述
    小鼠单克隆抗体[InA227] to H3 (H3N2)
  • 特异性
    ab82454 recognizes Influenza A haemagglutinin H3.
  • 经测试应用
    适用于: ICC/IF, WB, ELISA, Indirect ELISAmore details
  • 种属反应性
    Reacts with Influenza A H3 (H3N2)
  • 免疫原

    Influenza A/Shangdong/9/93 (strain H3N2) derived from allantoic fluid of 10 days old embryonated eggs.

  • 常规说明
    IgG1 for MAb InA227 IgG2a for MAb InA246

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 克隆
    单克隆
  • 克隆编号
    InA227
  • 骨髓瘤
    Sp2/0
  • 同种型
    IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab82454 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use at an assay dependent concentration. PubMed: 24835440
WB Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
Indirect ELISA Use at an assay dependent concentration.

靶标

  • 相关性
    Influenza A virus is a major public health threat. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. Hemagglutinin binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. It plays a major role in the determination of host range restriction and virulence and is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.
  • 细胞定位
    Virion membrane; Single-pass type I membrane protein. Potential host apical cell membrane; Single-pass type I membrane protein
  • 别名
    • Hemagglutinin antibody

Anti-H3 (H3N2) antibody [InA227] (ab82454)参考文献

This product has been referenced in:
  • Jeong HJ  et al. OsVIL1 controls flowering time in rice by suppressing OsLF under short days and by inducing Ghd7 under long days. Plant Cell Rep 35:905-20 (2016). Read more (PubMed: 26795142) »
  • Kwon HM  et al. An RNA aptamer that specifically binds to the glycosylated hemagglutinin of avian influenza virus and suppresses viral infection in cells. PLoS One 9:e97574 (2014). ICC/IF . Read more (PubMed: 24835440) »

See all 2 Publications for this product

Product Wall

Anti-H3 (H3N2) antibody [InA227] (ab82454) is specific to influenza A hemagglutinin H3, but we have not determined the exact epitope in hemagglutinin H3 it binds to.

ab82454 has been tested with following stains:


Strain
React...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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