Anti-Guanylate Cyclase抗体(ab53084)
Key features and details
- Rabbit polyclonal to Guanylate Cyclase
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-Guanylate Cyclase抗体 -
描述
兔多克隆抗体to Guanylate Cyclase -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Synthetic peptide derived from Human Guanylate Cyclase ß
-
阳性对照
- HuvEc cell extract; Paraffin-embedded human lung carcinoma tissue
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS
Without Mg+2 and Ca+2 -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab53084于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/300 - 1/1000. Detects a band of approximately 70 kDa (predicted molecular weight: 70 kDa).
|
|
IHC-P |
Use at an assay dependent concentration.
|
说明 |
---|
WB
1/300 - 1/1000. Detects a band of approximately 70 kDa (predicted molecular weight: 70 kDa). |
IHC-P
Use at an assay dependent concentration. |
靶标
-
相关性
Guanylate Cyclase is an heterodimer of an alpha and a beta chain. Its enzymatic activity transforms GTP to GMP releasing a diphosphate. It binds 1 or 2 hemes per heterodimer. It is activated by nitric oxide in the presence of magnesium or manganese ions. There are two types of guanylate cyclase: soluble form and membrane-associated receptor form. -
细胞定位
Cytoplasmic -
数据库链接
- Entrez Gene: 2974 Human
- Entrez Gene: 239134 Mouse
- Entrez Gene: 25206 Rat
- Omim: 603695 Human
- SwissProt: O75343 Human
- SwissProt: Q6XE41 Mouse
- SwissProt: P22717 Rat
-
别名
- GC SB2 antibody
- GCS beta 2 antibody
- Guanylate cyclase 1 soluble beta 2 antibody
- GUCY1B2 antibody
图片
-
All lanes : Anti-Guanylate Cyclase antibody (ab53084) at 1/300 dilution
Lane 1 : HuvEc cell extract
Lane 2 : HuvEc cell extract with peptide
Predicted band size: 70 kDa
Observed band size: 70 kDa -
Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Guanylate Cyclase ß antibody, ab53084, at 1/50 dilution.
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab53084 被引用在 1 文献中.
- Wu RY & Ma N Expression of nitric oxide synthase and guanylate cyclase in the human ciliary body and trabecular meshwork. Chin Med J (Engl) 125:129-33 (2012). WB, IHC-P ; Human . PubMed: 22340479