概述

  • 产品名称Anti-GTSE1抗体
    参阅全部 GTSE1 一抗
  • 描述
    兔多克隆抗体to GTSE1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide: IDLMTNTPDM NKNVAKPSPV VGQLIDLSSP LIQLSPEADK ENVDSPLLKF , corresponding to a region within internal sequence amino acids 690 - 739 of Human GTSE1 (NP_057510)

  • 阳性对照
    • MCF7 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab83316 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 77 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it co-localizes with cytoplasmic tubulin and microtubules. In response to DNA damage, GTSE1 accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. Overexpression of GTSE1 delays G2/M phase progression.
  • 细胞定位Cytoplasm. Note: Associated with microtubules
  • 数据库链接
  • 别名
    • B99 antibody
    • B99 homolog antibody
    • G 2 and S phase expressed 1 antibody
    • G two S phase expressed protein 1 antibody
    • GTSE 1 antibody
    see all

Anti-GTSE1 antibody 图像

  • Anti-GTSE1 antibody (ab83316) at 1 µg/ml (in 5% skim milk / PBS buffer) + MCF7 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 77 kDa
    Observed band size : 90 kDa (why is the actual band size different from the predicted?)

Anti-GTSE1 antibody (ab83316)参考文献

ab83316 has not yet been referenced specifically in any publications.

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