概述

  • 产品名称Anti-GTSE1抗体
    参阅全部 GTSE1 一抗
  • 描述
    兔多克隆抗体to GTSE1
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH conjugated synthetic peptide corresponding to a region within C terminal amino acids 691-720 of Human GTSE1.

  • 阳性对照
    • Hela cell lysate; Human brain tissue

性能

应用

Our Abpromise guarantee covers the use of ab103232 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 77 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 相关性GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it co-localizes with cytoplasmic tubulin and microtubules. In response to DNA damage, GTSE1 accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. Overexpression of GTSE1 delays G2/M phase progression.
  • 细胞定位Cytoplasm. Note: Associated with microtubules
  • 数据库链接
  • 别名
    • B99 antibody
    • B99 homolog antibody
    • G 2 and S phase expressed 1 antibody
    • G two S phase expressed protein 1 antibody
    • GTSE 1 antibody
    see all

Anti-GTSE1 antibody 图像

  • Anti-GTSE1 antibody (ab103232) at 1/100 dilution + Hela cell lysate at 35 µg

    Predicted band size : 77 kDa
  • ab103232, at 1/50 dilution, staining GTSE1 in formalin fixed, paraffin embedded Human brain tissue by Immunohistochemistry, using a peroxidase conjugated secondary antibody and DAB staining.

Anti-GTSE1 antibody (ab103232)参考文献

ab103232 has not yet been referenced specifically in any publications.

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