概述

  • 产品名称Anti-GTF3C4抗体
    参阅全部 GTF3C4 一抗
  • 描述
    兔多克隆抗体to GTF3C4
  • 经测试应用适用于: IHC-P, IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee
  • 免疫原

    A region between residues 625 and 675 of human GTF3C4 using the numbering given in entry NP_036336.1

  • 阳性对照
    • HeLa nuclear lysate

性能

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应用

Our Abpromise guarantee covers the use of ab74304 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/1000 - 1/5000. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
IP Use at 2-5 µg/mg of lysate.
  • 应用说明Is unsuitable for WB.
  • 靶标

    • 功能Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.
    • 序列相似性Belongs to the TFIIIC subunit 4 family.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • EC 2.3.1.48 antibody
      • FLJ21002 antibody
      • General transcription factor 3C 4 antibody
      • General transcription factor 3C polypeptide 4 antibody
      • General transcription factor IIIC, polypeptide 4, 90kDa antibody
      • GTF3C4 antibody
      • KAT12 antibody
      • MGC138450 antibody
      • OTTHUMP00000022434 antibody
      • TF3C delta antibody
      • TF3C-delta antibody
      • TF3C4_HUMAN antibody
      • TFIII90 antibody
      • TFIIIC 90 kDa subunit antibody
      • TFiiiC2 90 antibody
      • TFIIIC290 antibody
      • TFIIIC90 antibody
      • TFIIICdelta antibody
      • Transcription factor IIIC 90 kDa subunit antibody
      • Transcription factor IIIC subunit delta antibody
      see all

    Anti-GTF3C4 antibody 图像

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human prostate carcinoma tissue labelling GTF3C4 with ab74304 at 1/5000 (0.2µg/ml). Detection: DAB.
    • Detection of Human GTF3C4 by Immunoprecipitation. 1mg HeLa whole cell lysate loaded in lanes 1-4 with other antibodies that recognise an upstream epitope in lanes 1 and 2, ab74304 at 3 µg in lane 3 and control IgG in lane 4. Image shows immunoprecipitated GTF3C4 detected with post IP WB, loading 20% of IP and using ab74304 at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 3 seconds.

    Anti-GTF3C4 antibody (ab74304)参考文献

    ab74304 has not yet been referenced specifically in any publications.

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