概述

  • 产品名称Anti-GTF2IRD2抗体
    参阅全部 GTF2IRD2 一抗
  • 描述
    兔多克隆抗体to GTF2IRD2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 820-850 of Human GTF2IRD2

  • 阳性对照
    • K562 cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified through a protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab103946 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 107 kDa.

靶标

  • 相关性GTF2IRD2 N-terminal half contains a leucine zipper motif, followed by 2 helix-loop-helix motifs (I repeats) that share homology with the TFII-I family of transcription factors. The C-terminal half of GTF2IRD2A contains a CHARLIE8 transposable element-like sequence, including 3 transposase-related domains that may be functional, and a BED zinc finger DNA-binding motif. It is inferred to be a transcription factor based on the presence of GTF2I-like repeats (containing helix-loop-helix motifs), also found in other proteins such as GTF2IRD1 and GTF2I. GTF2IRD2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. There are six different isoforms, generated by alternative splicing.
  • 细胞定位Nuclear
  • 数据库链接
  • 别名
    • FLJ21423 antibody
    • FLJ37938 antibody
    • FP630 antibody
    • general transcription factor II i repeat domain 2 alpha antibody
    • general transcription factor II I repeat domain-containing protein 2A antibody
    • GTF2I repeat domain containing 2 antibody
    • GTF2I repeat domain containing protein 2A antibody
    • GTF2IRD2 alpha antibody
    • GTF2IRD2A antibody
    • MGC75203 antibody
    • Transcription factor GTF2IRD2 alpha antibody
    • transcription factor GTF2IRD2 antibody
    see all

Anti-GTF2IRD2 antibody 图像

  • Anti-GTF2IRD2 antibody (ab103946) at 1/100 dilution + K562 cell lysate at 35 µg

    Predicted band size : 107 kDa

Anti-GTF2IRD2 antibody (ab103946)参考文献

ab103946 has not yet been referenced specifically in any publications.

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