概述

  • 产品名称Anti-GSTA2抗体
    参阅全部 GSTA2 一抗
  • 描述
    小鼠单克隆抗体to GSTA2
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Sheep, Cow, Pig, Cynomolgus Monkey
  • 免疫原

    Recombinant fragment: MAEKPKLHYS NIRGRMESIR WLLAAAGVEF EEKFIKSAED LDKLRNDGYL MFQQVPMVEI DGMKLVQTRA ILNYIASKYN LYGKDIKEKA LIDMYIEGIA, corresponding to amino acids 1-100 of human GSTA2 (AAH02895) with a proprietary tag.

  • 阳性对照
    • The immunogen (recombinant protein fragment), human liver tissue lysate, HepG2 cell lysate

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab87967 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 26 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 相关性Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, which are located in a cluster on chromosome 6, are highly related and encode enzymes with glutathione peroxidase activity that function in the detoxification of lipid peroxidation products. Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis.
  • 细胞定位Cytoplasmic
  • 数据库链接
  • 别名
    • EC 2.5.1.18 antibody
    • Glutathione S transferase 2 antibody
    • Glutathione S transferase A2 antibody
    • Glutathione S-alkyltransferase A2 antibody
    • Glutathione S-aralkyltransferase A2 antibody
    • Glutathione S-aryltransferase A2 antibody
    • Glutathione S-transferase alpha 2 antibody
    • Glutathione S-transferase GT41A antibody
    • Glutathione S-transferase Ya-2 antibody
    • Glutathione S-transferase, alpha 2 (Yc2) antibody
    • GST 1b-1b antibody
    • GST A2-2 antibody
    • GST class alpha member 2 antibody
    • GST gamma antibody
    • GST HA subunit 2 antibody
    • GST Ya2 antibody
    • GST, class alpha, 2 antibody
    • GST2 antibody
    • Gst2-2 antibody
    • GSTA2 2 antibody
    • GSTA2-2 antibody
    • Gstc-2 antibody
    • Gstc2 antibody
    • GTA2 antibody
    • GTH2 antibody
    • HA subunit 2 antibody
    • Liver GST2 antibody
    • MGC10525 antibody
    • OTTHUMP00000017883 antibody
    • S-(hydroxyalkyl)glutathione lyase A2 antibody
    see all

Anti-GSTA2 antibody 图像

  • Anti-GSTA2 antibody (ab87967) at 5 µg/ml + the immunogen (tagged, recombinant human GSTA2 protein) at 0.2 µg

    Predicted band size : 26 kDa
    Observed band size : 37 kDa (why is the actual band size different from the predicted?)
  • Anti-GSTA2 antibody (ab87967) at 5 µg/ml + human liver tissue lysate at 50 µg

    Predicted band size : 26 kDa
    Observed band size : 26 kDa
  • Anti-GSTA2 antibody (ab87967) at 5 µg/ml + HepG2 cell lysate at 50 µg

    Predicted band size : 26 kDa
    Observed band size : 26 kDa
    Additional bands at : 50 kDa. We are unsure as to the identity of these extra bands.

Anti-GSTA2 antibody (ab87967)参考文献

This product has been referenced in:
  • Lee LY  et al. Activation of the Nrf2-ARE pathway in hepatocytes protects against steatosis in nutritionally induced non-alcoholic steatohepatitis in mice. Toxicol Sci 142:361-74 (2014). Read more (PubMed: 25294219) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"