Anti-GSK3 alpha (phospho S21)抗体(ab9765)

概述

  • 产品名称Anti-GSK3 alpha (phospho S21)抗体
    参阅全部 GSK3 alpha 一抗
  • 描述
    兔多克隆抗体to GSK3 alpha (phospho S21)
  • 特异性Specific for GSK 3 alpha isoform. Recognises a band at 52 kD.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide: RARTSpSFAEPC, corresponding to amino acids 16-25 of Human GSK3 alpha.

性能

应用

Our Abpromise guarantee covers the use of ab9765 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明Western blot: use at 1/1000.
    This product has been assayed by ELISA against 0.1µg of the immunizing peptide.
    A 1/1000 to 1/5000 dilution of the antibody is recommended for this assay.
    Not tested in other applications.

    Optimal dilutions / concentrations should be determined by the end user.
  • 靶标

    • 功能Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN.
    • 序列相似性Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
      Contains 1 protein kinase domain.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DKFZp686D0638 antibody
      • Glycogen synthase kinase 3 alpha antibody
      • Glycogen synthase kinase-3 alpha antibody
      • GSK 3 alpha antibody
      • GSK 3A antibody
      • GSK-3 alpha antibody
      • Gsk3a antibody
      • GSK3A_HUMAN antibody
      • GSK3alpha antibody
      • Serine/threonine protein kinase GSK3A antibody
      see all

    Anti-GSK3 alpha (phospho S21) antibody 图像

    • This image is courtesy of Angela Carter, Experimental Therapeutics, Ontario Cancer Inst, Toronto, Canada

      Rabbit polyclonal to phospho GSK alpha (Ser 21) at 1/1000 on 293T cell extract shows a band at 52 kD.
      Cells were serum starved for 24 hours:

      Lane 1 : control
      Lane 2 : treated with IGF-1 (100 ng/ml) for 20 min
      Lane 3 : pre-treated with 10 uM LY294002 (selective PI3K inhibitor) and treated with IGF-1 (100 ng/ml) for 20 min

      Rabbit polyclonal to phospho GSK alpha (Ser 21) at 1/1000 on 293T cell extract shows a band at 52 kD.
      Cells were serum starved for 24 hours:

      Lane 1 : control
      Lane 2 : treated with IGF-1 (100 ng/ml) for 20 min
      Lane 3 : pre-treated with 10 uM LY294002 (selective PI3K inhibitor) and treated with IGF-1 (100 ng/ml) for 20 min

    Anti-GSK3 alpha (phospho S21) antibody (ab9765)参考文献

    ab9765 has not yet been referenced specifically in any publications.

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