1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
功能Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.
疾病相关Autoantigen in rheumatoid arthritis.
序列相似性Belongs to the heat shock protein 70 family.
细胞定位Endoplasmic reticulum lumen. Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
ab103336 at 1/50 dilution staining GRP78 BiP in formalin-fixed and paraffin-embedded Human lung carcinoma by Immunohistochemistry, followed by peroxidase conjugation of the secondary antibody and DAB detection.
Anti-GRP78 BiP antibody (ab103336)参考文献
has not yet been referenced specifically in any publications.