Anti-GRP78 BiP抗体[10C3] (DyLight® 488) (ab115638)

概述

  • 产品名称Anti-GRP78 BiP抗体[10C3] (DyLight® 488)
    参阅全部 GRP78 BiP 一抗
  • 描述
    小鼠单克隆抗体[10C3] to GRP78 BiP (DyLight® 488)
  • 偶联物DyLight® 488. Ex: 493nm, Em: 518nm
  • 特异性Recognizes proteins containing the KDEL sequence.
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Rat, Human
    预测可用于: Bird, Plants, all Mammals
  • 免疫原

    Synthetic peptide corresponding to Rat GRP78 BiP aa 649-654.
    Sequence:

    SEKDEL

  • 阳性对照
    • Jurkat cells.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号10C3
  • 同种型IgG2a
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab115638 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt 1/20.

靶标

  • 功能Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.
  • 疾病相关Autoantigen in rheumatoid arthritis.
  • 序列相似性Belongs to the heat shock protein 70 family.
  • 细胞定位Endoplasmic reticulum lumen. Melanosome. Cytoplasm. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 78 kDa glucose regulated protein antibody
    • 78 kDa glucose-regulated protein antibody
    • AL022860 antibody
    • AU019543 antibody
    • BIP antibody
    • D2Wsu141e antibody
    • D2Wsu17e antibody
    • Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78 antibody
    • Endoplasmic reticulum lumenal Ca2+ binding protein grp78 antibody
    • Epididymis secretory sperm binding protein Li 89n antibody
    • FLJ26106 antibody
    • Glucose Regulated Protein 78kDa antibody
    • GRP 78 antibody
    • GRP-78 antibody
    • GRP78 antibody
    • GRP78_HUMAN antibody
    • Heat shock 70 kDa protein 5 antibody
    • Heat Shock 70kDa Protein 5 antibody
    • Heat shock protein family A (Hsp70) member 5 antibody
    • HEL S 89n antibody
    • Hsce70 antibody
    • HSPA 5 antibody
    • HSPA5 antibody
    • Immunoglobulin Heavy Chain Binding Protein antibody
    • Immunoglobulin heavy chain-binding protein antibody
    • mBiP antibody
    • MIF2 antibody
    • Sez7 antibody
    see all

Anti-GRP78 BiP antibody [10C3] (DyLight® 488) 图像

  • ab115638 at 10µg/ml staining GRP78 in 506 Jurkat cells by Flow cytometry (shown in green).
    Grey: unstained;Yellow: isotype control.

Anti-GRP78 BiP antibody [10C3] (DyLight® 488) (ab115638)参考文献

ab115638 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. This antibody has not been tested without permeabilization. Due to its intracellular localization, the laboratory skeptical that it would work this way.

I hope this information is helpful to you. Please do not hesi...

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Thank you for contacting us regarding the flow cytometry protocol for ab115638.

I do wish to apologize for the delay in getting this information to you. The protocol used by the lab is attached.

I hope this information is hel...

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Thank you for contacting us. Unofrtunately we do not have the Dylight 488 isotype control available in our catalog.


I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information...

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Thank you for contacting Abcam and for your interest in ab115638.


As we discussed, I have updated the datasheet to reflect that human is a tested species guaranteed by our Abpromise. I apologize for the discrepancy and for any confusion t...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"