概述

  • 产品名称Anti-GRHL2抗体
    参阅全部 GRHL2 一抗
  • 描述
    小鼠多克隆抗体to GRHL2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length human GRHL2 protein (NP_079191.1, 1 a.a. ~ 625 a.a)

  • 阳性对照
    • GRHL2 transfected 293T lysate.

性能

应用

Our Abpromise guarantee covers the use of ab69052 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 75 kDa (predicted molecular weight: 71 kDa).

靶标

  • 功能May function as a transcription factor.
  • 组织特异性Highly expressed in placenta, prostate, brain and kidney. Lower-level expression in a variety of epithelial tissues such as thymus, kidney, lung, salivary gland, mammary gland and digestive tract. Expressed in the cochlear.
  • 疾病相关Defects in GRHL2 are the cause of deafness autosomal dominant type 28 (DFNA28) [MIM:608641]. DFNA28 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. DFNA28 is characterized by mild to moderate hearing loss across most frequencies that progressed to severe loss in the higher frequencies by the fifth decade. Age at onset varied, with the earliest case documented at 7 years of age.
  • 序列相似性Belongs to the grh/CP2 family. Grainyhead subfamily.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BOM antibody
    • Brother of mammalian grainyhead antibody
    • Deafness autosomal dominant 28 antibody
    • DFNA28 antibody
    • ECTDS antibody
    • FLJ11172 antibody
    • FLJ13782 antibody
    • Grainyhead like 2 (Drosophila) antibody
    • Grainyhead like 2 antibody
    • Grainyhead like protein 2 homolog antibody
    • Grainyhead like transcription factor 2 antibody
    • Grainyhead-like protein 2 homolog antibody
    • GRHL 2 antibody
    • GRHL2 antibody
    • GRHL2_HUMAN antibody
    • MGC149294 antibody
    • MGC149295 antibody
    • RGD1561191 antibody
    • TFCP2L3 antibody
    • Transcription factor CP2 like 3 antibody
    • Transcription factor CP2-like 3 antibody
    see all

Anti-GRHL2 antibody 图像

  • All lanes : Anti-GRHL2 antibody (ab69052) at 1/500 dilution

    Lane 1 : GRHL2 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 71 kDa
    Observed band size : 75 kDa (why is the actual band size different from the predicted?)

Anti-GRHL2 antibody (ab69052)参考文献

ab69052 has not yet been referenced specifically in any publications.

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