概述

  • 产品名称Anti-GRF2抗体
    参阅全部 GRF2 一抗
  • 描述
    兔多克隆抗体to GRF2
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from an internal sequence of Human GRF2.

  • 阳性对照
    • Human breast carcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab111061 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS.
  • 组织特异性Ubiquitously expressed in adult and fetus. Expression is high in adult skeletal muscle and placenta and in fetal brain and heart. Low levels of expression in adult and fetal liver.
  • 序列相似性Contains 1 N-terminal Ras-GEF domain.
    Contains 1 Ras-GEF domain.
  • Information by UniProt
  • 数据库链接
  • 形式It localizes to cytoplasm and endosomes.
  • 别名
    • C3G antibody
    • C3G protein antibody
    • CRK SH3 binding GNRP antibody
    • CRK SH3-binding GNRP antibody
    • DKFZp781P1719 antibody
    • GRF 2 antibody
    • GRF2 antibody
    • Guanine nucleotide releasing factor 2 (specific for crk proto oncogene) antibody
    • Guanine nucleotide releasing factor 2 antibody
    • Guanine nucleotide-releasing factor 2 antibody
    • OTTHUMP00000064558 antibody
    • Protein C3G antibody
    • Rap guanine nucleotide exchange factor (GEF) 1 antibody
    • Rap guanine nucleotide exchange factor 1 antibody
    • RAPGEF 1 antibody
    • RAPGEF1 antibody
    • RPGF1_HUMAN antibody
    see all

Anti-GRF2 antibody 图像

  • ab111061 at 1/50 dilution staining GRF2 in paraffin-embedded Human Breast carcinoma tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

Anti-GRF2 antibody (ab111061)参考文献

ab111061 has not yet been referenced specifically in any publications.

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