概述

  • 产品名称
  • 描述
    山羊多克隆抗体to GRB7
  • 经测试应用
    适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide: ELDLSPPHLSSSPE, corresponding to amino acids 2-15 of Human GRB 7.

  • 阳性对照
    • A431 lysate
  • 常规说明
    Principal Names - GRB7; growth factor receptor-bound protein 7 Official Gene Symbol - GRB7 GenBank Accession Number – NP_005301 LocusLink ID - 2886 Gene Ontology terms - oncogenesis; SH3/SH2 adaptor protein; EGF receptor signalling pathway

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, 0.5mg/ml Tris, pH 7.3
  • Concentration information loading...
  • 纯度
    IgG fraction
  • 纯化说明
    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab2630 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明
    ELISA: 1/32000.
    WB: Use at a concentration of 1 - 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Interacts with the cytoplasmic domain of the epidermal growth factor receptor which is then inhibited. The interaction is mediated by the SH2 domain. Also binds to ERBB2.
    • 序列相似性
      Belongs to the GRB7/10/14 family.
      Contains 1 PH domain.
      Contains 1 Ras-associating domain.
      Contains 1 SH2 domain.
    • 翻译后修饰
      Phosphorylated on tyrosine residues.
    • Information by UniProt
    • 数据库链接
    • 别名
      • B47 antibody
      • Epidermal growth factor receptor GRB 7 antibody
      • Epidermal growth factor receptor GRB-7 antibody
      • GRB7 adapter protein antibody
      • GRB7 antibody
      • GRB7_HUMAN antibody
      • Growth factor receptor bound protein 7 antibody
      • Growth factor receptor-bound protein 7 antibody
      • OTTHUMP00000164349 antibody
      • OTTHUMP00000164350 antibody
      • OTTHUMP00000164351 antibody
      • OTTHUMP00000164352 antibody
      see all

    实验方案

    文献

    This product has been referenced in:
    • Tsichlaki E & FitzHarris G Nucleus downscaling in mouse embryos is regulated by cooperative developmental and geometric programs. Sci Rep 6:28040 (2016). Read more (PubMed: 27320842) »

    See 1 Publication for this product

    客户评价及客户问答

    There are currently no Customer reviews or Questions for ab2630.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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