Anti-GRB2抗体[R11] (ab232)

概述

  • 产品名称Anti-GRB2抗体[R11]
    参阅全部 GRB2 一抗
  • 描述
    小鼠单克隆抗体[R11] to GRB2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    The immunogen peptide was selected from a region within the last 200 aa of the protein.

性能

应用

Our Abpromise guarantee covers the use of ab232 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100.

靶标

  • 功能Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
    Isoform GRB3-3 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform GRB3-3 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
  • 序列相似性Belongs to the GRB2/sem-5/DRK family.
    Contains 1 SH2 domain.
    Contains 2 SH3 domains.
  • 结构域The SH3 domains mediate interaction with RALGPS1 and SHB.
  • 细胞定位Golgi apparatus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Abundant SRC homology antibody
    • Adapter protein GRB2 antibody
    • ASH antibody
    • Ash protein antibody
    • EGFRBP GRB2 antibody
    • Epidermal growth factor receptor binding protein antibody
    • Epidermal growth factor receptor binding protein GRB2 antibody
    • GRB 2 antibody
    • GRB2 adapter protein antibody
    • Grb2 antibody
    • GRB2_HUMAN antibody
    • Grb3 3 antibody
    • Growth factor receptor bound protein 2 antibody
    • Growth factor receptor bound protein 3 antibody
    • Growth factor receptor-bound protein 2 antibody
    • HT027 antibody
    • MST084 antibody
    • MSTP084 antibody
    • NCKAP2 antibody
    • OTTHUMP00000166096 antibody
    • OTTHUMP00000166097 antibody
    • OTTHUMP00000166098 antibody
    • Protein ash antibody
    • SEM5 antibody
    • SH2/SH3 adapter GRB2 antibody
    see all

Anti-GRB2 antibody [R11] (ab232)参考文献

ab232 has not yet been referenced specifically in any publications.

Product Wall

Dear Gosta This is an externally sourced product so we are not able to offer you the supernatant, as this option is not available to us.

The concentration for both ab232 and ab233 have not specifically been determined as both of them are tissue culture supernatants. However, the approximate concentration for each of them should fall in the region of 10-50ug/ml. I shall amend our datashe...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"