Anti-GRB2抗体- N-terminal (ab80065)

概述

  • 产品名称Anti-GRB2抗体- N-terminal
    参阅全部 GRB2 一抗
  • 描述
    兔多克隆抗体to GRB2 - N-terminal
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the N terminal region of Human GRB2.

  • 阳性对照
    • HepG2 cell line lysate. Mouse spleen tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab80065 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50 - 1/100. Predicted molecular weight: 25 kDa.
ELISA 1/1000.

靶标

  • 功能Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway.
    Isoform GRB3-3 does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Isoform GRB3-3 acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
  • 序列相似性Belongs to the GRB2/sem-5/DRK family.
    Contains 1 SH2 domain.
    Contains 2 SH3 domains.
  • 结构域The SH3 domains mediate interaction with RALGPS1 and SHB.
  • 细胞定位Golgi apparatus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Abundant SRC homology antibody
    • Adapter protein GRB2 antibody
    • ASH antibody
    • Ash protein antibody
    • EGFRBP GRB2 antibody
    • Epidermal growth factor receptor binding protein antibody
    • Epidermal growth factor receptor binding protein GRB2 antibody
    • GRB 2 antibody
    • GRB2 adapter protein antibody
    • Grb2 antibody
    • GRB2_HUMAN antibody
    • Grb3 3 antibody
    • Growth factor receptor bound protein 2 antibody
    • Growth factor receptor bound protein 3 antibody
    • Growth factor receptor-bound protein 2 antibody
    • HT027 antibody
    • MST084 antibody
    • MSTP084 antibody
    • NCKAP2 antibody
    • OTTHUMP00000166096 antibody
    • OTTHUMP00000166097 antibody
    • OTTHUMP00000166098 antibody
    • Protein ash antibody
    • SEM5 antibody
    • SH2/SH3 adapter GRB2 antibody
    see all

Anti-GRB2 antibody - N-terminal 图像

  • Anti-GRB2 antibody - N-terminal (ab80065) at 1/50 dilution + HepG2 cell line lysate at 35 µg

    Predicted band size : 25 kDa
    Observed band size : 25 kDa
    Additional bands at : 37 kDa. We are unsure as to the identity of these extra bands.
  • Anti-GRB2 antibody - N-terminal (ab80065) at 1/50 dilution + mouse spleen tissue lysate at 35 µg

    Predicted band size : 25 kDa
    Observed band size : 25 kDa
    Additional bands at : 85 kDa. We are unsure as to the identity of these extra bands.

Anti-GRB2 antibody - N-terminal (ab80065)参考文献

ab80065 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab80065.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"