概述

  • 产品名称Anti-Granzyme H抗体
    参阅全部 Granzyme H 一抗
  • 描述
    小鼠多克隆抗体to Granzyme H
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length protein corresponding to Human Granzyme H.
    Database link: NP_219491.1

  • 阳性对照
    • Human spleen tissue lysate, Granzyme H transfected 293T cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab89607 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa.

靶标

  • 功能Cytotoxic chymotrypsin-like serine protease with preference for bulky and aromatic residues at the P1 position and acidic residues at the P3' and P4' sites. Probably necessary for target cell lysis in cell-mediated immune responses. Participates in the antiviral response via direct cleavage of several proteins essential for viral replication.
  • 组织特异性Constituvely expressed in NK cells.
  • 序列相似性Belongs to the peptidase S1 family. Granzyme subfamily.
    Contains 1 peptidase S1 domain.
  • 细胞定位Cytoplasmic granule. Cytoplasmic granules of cytolytic T-lymphocytes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cathepsin G like 2 antibody
    • Cathepsin G-like 2 antibody
    • CCP X antibody
    • CCP-X antibody
    • CGL 2 antibody
    • CGL2 antibody
    • CSP C antibody
    • CSP-C antibody
    • CTLA1 antibody
    • CTSGL2 antibody
    • Cytotoxic serine protease C antibody
    • Cytotoxic T lymphocyte associated serine esterase 1 antibody
    • Cytotoxic T lymphocyte proteinase antibody
    • Cytotoxic T-lymphocyte proteinase antibody
    • EC 3.4.21.- antibody
    • GRAH_HUMAN antibody
    • Granzyme H (cathepsin G-like 2, protein h-CCPX) antibody
    • Granzyme H antibody
    • GZMH antibody
    • Protein h CCPX antibody
    see all

Anti-Granzyme H antibody 图像

  • Anti-Granzyme H antibody (ab89607) at 1 µg/ml + Human spleen tissue lysate at 50 µg

    Predicted band size : 27 kDa
    Observed band size : 23 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-Granzyme H antibody (ab89607) at 1 µg/ml

    Lane 1 : GZMH transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 27 kDa
    Observed band size : 26 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 33 kDa. We are unsure as to the identity of these extra bands.

Anti-Granzyme H antibody (ab89607)参考文献

ab89607 has not yet been referenced specifically in any publications.

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