概述

  • 产品名称Anti-Grancalcin抗体
  • 描述
    小鼠单克隆抗体to Grancalcin
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-218 of Human Grancalcin

性能

应用

Our Abpromise guarantee covers the use of ab57040 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性Grancalcin is a calcium binding protein abundant in neutrophils and macrophages. It belongs to the penta EF hand subfamily of proteins which includes sorcin, calpain, and ALG2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule membrane fusion and degranulation.
    • 细胞定位50% cytoplasmic, the remainder being attached to the membranes and granules.
    • 数据库链接
    • 别名
      • GCA antibody
      • GCL antibody

    Anti-Grancalcin antibody 图像



    • Predicted band size : 24 kDa
      Grancalcin antibody (ab57040) at 1ug/lane + MCF-7 cell lysate at 25ug/lane.

    Anti-Grancalcin antibody (ab57040)参考文献

    ab57040 has not yet been referenced specifically in any publications.

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