Anti-Gram Negative Endotoxin抗体[11-222.4] (ab41201)

概述

  • 产品名称
    Anti-Gram Negative Endotoxin抗体[11-222.4]
  • 描述
    小鼠单克隆抗体[11-222.4] to Gram Negative Endotoxin
  • 经测试应用
    适用于: ELISAmore details
  • 种属反应性
    Sh. sonnei, S. typhimurium, S. marcescens, P. mirabilis, P. vulgaris, A. calcoaceticus
  • 免疫原

    Escherichia coli O:111 B4 J5 cells

  • 常规说明


    This antibody may be used in immunoassays to detect and quantitate gram negative endotoxin or cells that express endotoxin.

    Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by June 2019 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause. 

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度
    Protein G purified
  • Primary antibody说明
    This antibody may be used in immunoassays to detect and quantitate gram negative endotoxin or cells that express endotoxin.
  • 克隆
    单克隆
  • 克隆编号
    11-222.4
  • 同种型
    IgG2a
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab41201 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1600.

靶标

  • 相关性
    Endotoxins are part of the outer membrane of the cell wall of gram negative bacteria. Endotoxins are invariably associated with gram negative bacteria whether the organisms are pathogens or not. Although the term "endotoxin" is occasionally used to refer to any cell associated bacterial toxin, it is properly reserved to refer to the lipopolysaccharide complex associated with the outer membrane of gram-negative bacteria such as E. coli, Salmonella, Shigella, Pseudomonas, Neisseria, Haemophilus, and other leading pathogens. The biological activity of endotoxins are associated with lipopolysaccharide (LPS). Toxicity is associated with the lipid component (Lipid A) and immunogenicity is associated with the polysaccharide components. The cell wall antigens (O antigens) of gram negative bacteria are components of LPS. LPS elicits a variety of inflammatory responses in an animal. Because it activates complement by the alternative (properdin) pathway, it is often part of the pathology of gram negative bacterial infections.
  • 细胞定位
    Cell Membrane
  • 别名
    • E coli LPS antibody

文献

ab41201 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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