概述

  • 产品名称Anti-GPSM1抗体
    参阅全部 GPSM1 一抗
  • 描述
    兔多克隆抗体to GPSM1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH conjugated synthetic peptide between amino acids 446-476 from the central region of Human GPSM1 (NP_056412.4 , NP_001139110.1 , NP_001139111.1).

  • 阳性对照
    • NCI-H460 cell line lysate

性能

应用

Our Abpromise guarantee covers the use of ab113040 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 75 kDa.

靶标

  • 功能Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction.
  • 组织特异性Expressed in intestinal cells.
  • 序列相似性Belongs to the GPSM family.
    Contains 4 GoLoco domains.
    Contains 9 TPR repeats.
  • 结构域The GoLoco domains mediate interaction with G(i/o) alpha (By similarity). The GoLoco domains are essential for the GDI activity toward G(i/o) alpha.
  • 翻译后修饰Phosphorylation regulates interaction with G(i/o) alpha.
  • 细胞定位Cytoplasm > cytosol. Endoplasmic reticulum membrane. Golgi apparatus membrane. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Activator of G-protein signaling 3 antibody
    • AGS3 antibody
    • AGS3 homolog antibody
    • C10a antibody
    • G protein signaling modulator 1 (AGS3 like, C. elegans) antibody
    • G-protein-signaling modulator 1 antibody
    • GPSM1 antibody
    • GPSM1_HUMAN antibody
    see all

Anti-GPSM1 antibody 图像

  • Anti-GPSM1 antibody (ab113040) at 1/100 dilution + NCI-H460 cell line lysate at 35 µg

    Predicted band size : 75 kDa

Anti-GPSM1 antibody (ab113040)参考文献

ab113040 has not yet been referenced specifically in any publications.

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