概述

  • 产品名称
  • 描述
    兔多克隆抗体to GPRC5C
  • 特异性
    Detects endogenous levels of total GPRC5C protein.
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Synthetic peptide derived from an internal region of Human GPRC5C

  • 阳性对照
    • Cos-7 cell extract RAW264.7 cell extract

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab75499 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 48 kDa).
ELISA 1/5000.

靶标

  • 功能
    This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
  • 组织特异性
    Expression is highest in the periphery, particularly in the stomach, but also in the kidney, liver, pancreas, and prostate. In brain, levels of expression are generally lower than in the periphery, with the exception of cerebellum, spinal cord, and dorsal root ganglia (DRG).
  • 序列相似性
    Belongs to the G-protein coupled receptor 3 family.
  • 翻译后修饰
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位
    Cell membrane. Cytoplasmic vesicle membrane. Localized in the plasma membrane and perinuclear vesicles.
  • Information by UniProt
  • 数据库链接
  • 别名
    • G protein coupled receptor family C group 5 member C antibody
    • G-protein coupled receptor family C group 5 member C antibody
    • GPC5C_HUMAN antibody
    • GPCR5C antibody
    • Gprc5c antibody
    • MGC131820 antibody
    • Orphan G protein coupled receptor antibody
    • RAIG-3 antibody
    • RAIG3 antibody
    • Retinoic acid responsive gene protein antibody
    • Retinoic acid-induced gene 3 protein antibody
    see all

Anti-GPRC5C antibody 图像

  • All lanes : Anti-GPRC5C antibody (ab75499) at 1/500 dilution

    Lane 1 : RAW264.7 cell extract
    Lane 2 : Cos-7 cell extract
    Lane 3 : RAW264.7 cell extract with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 48 kDa
    Observed band size : 48 kDa
    Additional bands at : 100 kDa. We are unsure as to the identity of these extra bands.

实验方案

Anti-GPRC5C antibody (ab75499)参考文献

ab75499 has not yet been referenced specifically in any publications.

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