概述

  • 产品名称
  • 描述
    兔多克隆抗体to GPRC5C
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide conjugated to KLH, from the C-terminal cytoplasmic domain of Human GPRC5C (NP_061123.3).

  • 阳性对照
    • Human Pancreas tissue.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at -80°C.
  • 存储溶液
    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度
    Protein A purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab115616 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 3 - 32 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能
    This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
  • 组织特异性
    Expression is highest in the periphery, particularly in the stomach, but also in the kidney, liver, pancreas, and prostate. In brain, levels of expression are generally lower than in the periphery, with the exception of cerebellum, spinal cord, and dorsal root ganglia (DRG).
  • 序列相似性
    Belongs to the G-protein coupled receptor 3 family.
  • 翻译后修饰
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位
    Cell membrane. Cytoplasmic vesicle membrane. Localized in the plasma membrane and perinuclear vesicles.
  • Information by UniProt
  • 数据库链接
  • 别名
    • G protein coupled receptor family C group 5 member C antibody
    • G-protein coupled receptor family C group 5 member C antibody
    • GPC5C_HUMAN antibody
    • GPCR5C antibody
    • Gprc5c antibody
    • MGC131820 antibody
    • Orphan G protein coupled receptor antibody
    • RAIG-3 antibody
    • RAIG3 antibody
    • Retinoic acid responsive gene protein antibody
    • Retinoic acid-induced gene 3 protein antibody
    see all

图片

  • ab115,616 at 3-32µg/ml, staining GPRC5C in Formalin-fixed, Paraffin-embedded Human pancreas tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

文献

ab115616 has not yet been referenced specifically in any publications.

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