概述

  • 产品名称
  • 描述
    兔多克隆抗体to GPR73B
  • 特异性
    This antibody reacts specifically with human GPR73B.
  • 经测试应用
    适用于: IHC-P, IHC-Fr, Flow Cyt, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from N terminal region of human GPR73B

性能

应用

Our Abpromise guarantee covers the use of ab42805 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50.
IHC-Fr 1/50.
Flow Cyt 1/100.
WB 1/200. Predicted molecular weight: 44 kDa.

靶标

  • 功能
    Receptor for prokineticin 2. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase.
  • 组织特异性
    Expressed in the ileocecum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary and brain.
  • 疾病相关
    Hypogonadotropic hypogonadism 3 with or without anosmia
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • B830005M06Rik antibody
    • dJ680N4.3 antibody
    • EG-VEGRF2 antibody
    • G protein coupled receptor 73 like 1 antibody
    • G protein coupled receptor I5E antibody
    • G-protein coupled receptor 73-like 1 antibody
    • GPR73b antibody
    • GPR73L1 antibody
    • GPRg2 antibody
    • HH3 antibody
    • KAL3 antibody
    • PK R2 antibody
    • PK-R2 antibody
    • PKR2 antibody
    • PKR2_HUMAN antibody
    • Prokineticin receptor 2 antibody
    • PROKR2 antibody
    see all

图片

  • ab42805 staining GPR73B in umbilical cord (top) and placental villi (bottom) sections by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). On the right are negative controls

    Ho: Hofbauer cells; Ec: Endothelial cells; Bv: Blood vessels.

文献

This product has been referenced in:
  • Urayama K  et al. Transgenic myocardial overexpression of prokineticin receptor-2 (GPR73b) induces hypertrophy and capillary vessel leakage. Cardiovasc Res 81:28-37 (2009). Read more (PubMed: 18806277) »

See 1 Publication for this product

客户评价及客户问答

I have just been informed that the information that I gave yesterday in regards to ab90622 was incorrect. The homology of the chick protein is more than 85% homology with the region of the mouse protein from which the antibody was raised. We would ther...

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I have now received confirmation on the homology of the final antibody ab90622 and unfortunately the sequence similarity with the immunogen is again very poor, we would therefore not expect this antibody to recognise the chick protein either. Y...

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Thank you for contacting us. I have looked into the 3 antibodies (ab42805, ab90622, ab99453) that we have against GPR73B to see which ones are most likely to also recognise chick GPR73B. ab42805 and ab99453 are both raised against the N-termina...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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