概述

  • 产品名称Anti-GPR56抗体
    参阅全部 GPR56 一抗
  • 描述
    兔多克隆抗体to GPR56
  • 经测试应用适用于: WB, ELISA, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from the an internal sequence of Human GPR56

  • 阳性对照
    • WB: extracts from K562 cells. ICC/IF: MCF-7 cells.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab77515 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 78 kDa.
ELISA 1/20000.
ICC/IF 1/500 - 1/1000.

靶标

  • 功能Could be involved in cell-cell interactions.
  • 组织特异性Widely distributed with highest levels found in thyroid gland, brain and heart. Expressed in a great number of tumor cells.
  • 疾病相关Polymicrogyria, bilateral frontoparietal (BFPP) [MIM:606854]: A malformation of the cortex in which the brain surface is irregular and characterized by an excessive number of small gyri with abnormal lamination, most severe in the frontoparietal regions. BFPP clinical manifestations include developmental and psychomotor delay, cerebellar and pyramidal signs, truncal ataxia, seizures, hyperreflexia. Polymicrogyria is a heterogeneous disorder, considered to be the result of postmigratory abnormal cortical organization. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • 序列相似性Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 1 GPS domain.
  • 翻译后修饰The endogenous protein is proteolytically cleaved into 2 subunits, an extracellular subunit and a seven-transmembrane subunit.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 7 transmembrane protein with no EGF like N terminal domains 1 antibody
    • BFPP antibody
    • DKFZp781L1398 antibody
    • EGF TM7 like antibody
    • G protein coupled receptor 56 antibody
    • G-protein coupled receptor 56 antibody
    • GPR 56 antibody
    • Gpr56 antibody
    • GPR56_HUMAN antibody
    • Polymicrogyria bilateral frontoparietal antibody
    • Protein TM7XN1 antibody
    • TM7LN4 antibody
    • TM7XN1 antibody
    • TM7XN1 protein antibody
    see all

Anti-GPR56 antibody 图像

  • All lanes : Anti-GPR56 antibody (ab77515) at 1/500 dilution

    Lane 1 : Extracts from K562 cells
    Lane 2 : Extracts from K562 cells with immunizing peptide at 5 µg

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 78 kDa
    Observed band size : 78 kDa
  • Immunofluorescence analysis of MCF-7 cells using 1/500 - 1/1000 ab77515
    Left image: untreated.
    Right image: after pre-incubation twith immunizing peptide.

Anti-GPR56 antibody (ab77515)参考文献

ab77515 has not yet been referenced specifically in any publications.

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