概述

  • 产品名称
  • 描述
    兔多克隆抗体to GPNMB
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Horse, Guinea pig, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 143 - 192 of Human GPNMB (NP_001005340).

  • 阳性对照
    • PANC1 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab98856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 64 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Could be a melanogenic enzyme.
  • 组织特异性
    Not restricted to the melanocytic lineage.
  • 序列相似性
    Belongs to the PMEL/NMB family.
    Contains 1 PKD domain.
  • 发展阶段
    Expression in poorly metastatic melanoma cell lines; no expression in highly metastatic melanoma cell lines.
  • 细胞定位
    Membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Glycoprotein (transmembrane) nmb antibody
    • Glycoprotein nmb antibody
    • Glycoprotein nmb like protein antibody
    • Gpnmb antibody
    • GPNMB_HUMAN antibody
    • HGFIN antibody
    • NMB antibody
    • Osteoactivin antibody
    • Transmembrane glycoprotein antibody
    • Transmembrane glycoprotein HGFIN antibody
    • Transmembrane glycoprotein NMB antibody
    see all

图片

  • Anti-GPNMB antibody (ab98856) at 1 µg/ml + PANC1 cell lysate at 10 µg

    Predicted band size : 64 kDa

实验方案

文献

This product has been referenced in:
  • Epple LM  et al. Medulloblastoma exosome proteomics yield functional roles for extracellular vesicles. PLoS One 7:e42064 (2012). WB . Read more (PubMed: 22848702) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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