Anti-GPCR GPRC5B抗体(ab75427)


  • 产品名称
    Anti-GPCR GPRC5B抗体
    参阅全部 GPCR GPRC5B 一抗
  • 描述
    兔多克隆抗体to GPCR GPRC5B
  • 经测试应用
    适用于: WB, ELISA, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from an internal sequence of human GPCR GPRC5B.

  • 阳性对照
    • Extracts from HUVEC, 293 and Jurkat cells. MCF-7 cells.



Our Abpromise guarantee covers the use of ab75427 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 45 kDa.
ELISA 1/5000.
ICC/IF 1/500 - 1/1000.


  • 功能
    Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
  • 组织特异性
    Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte. According to PubMed:10945465, highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal chord as well as in dorsal root ganglia (DRG). In the periphery, expression levels are relatively low, compared to the CNS, with the strongest expression detected in pancreas, testis, uterus, and stomach.
  • 序列相似性
    Belongs to the G-protein coupled receptor 3 family.
  • 细胞定位
    Cell membrane. Cytoplasmic vesicle membrane. Localized in the plasma membrane and perinuclear vesicles.
  • Information by UniProt
  • 数据库链接
  • 别名
    • A 69G12.1 antibody
    • A-69G12.1 antibody
    • G protein coupled receptor family C group 1 member B antibody
    • G protein coupled receptor family C group 5 member B antibody
    • G-protein coupled receptor family C group 5 member B antibody
    • GPC5B_HUMAN antibody
    • Gprc5b antibody
    • LOC51704 antibody
    • RAIG-2 antibody
    • RAIG2 antibody
    • Retinoic acid responsive gene protein antibody
    • Retinoic acid-induced gene 2 protein antibody
    see all

Anti-GPCR GPRC5B antibody 图像

  • ab75427 staining MCF7 cells at 1/500 dilution, in the absence and presence of the immunising peptide
  • All lanes : Anti-GPCR GPRC5B antibody (ab75427) at 1/500 dilution

    Lane 1 : extracts from HUVEC cells
    Lane 2 : extracts from 293 cells
    Lane 3 : extracts from Jurkat cells
    Lane 4 : extracts from Jurkat cells with immunising peptide at 5 µg

    Lysates/proteins at 5 µg per lane.

    Predicted band size : 45 kDa
    Observed band size : 48 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 70 kDa. We are unsure as to the identity of these extra bands.

Anti-GPCR GPRC5B antibody (ab75427)参考文献

ab75427 has not yet been referenced specifically in any publications.

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