Anti-GPCR GPR43抗体(ab124272)

概述

  • 产品名称
    Anti-GPCR GPR43抗体
    参阅全部 GPCR GPR43 一抗
  • 描述
    兔多克隆抗体to GPCR GPR43
  • 宿主
    Rabbit
  • 经测试应用
    适用于: ELISA, IHC-P, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to the C terminal region of Human GPCR GPR43.

  • 阳性对照
    • Human tonsil tissue; COS7 cells

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 50% Glycerol, 0.88% Sodium chloride
    Note: PBS is without Mg2+ and Ca2+
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab124272 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
IHC-P Use a concentration of 5 µg/ml.
ICC/IF 1/100 - 1/500.

靶标

  • 功能
    Receptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is acetate= propionate = butyrate > pentanoate = formate.
  • 组织特异性
    Expressed at relatively high levels in peripheral blood leukocytes and, to lesser, extent, in spleen.
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Fatty acid receptor 2 antibody
    • FFA2R antibody
    • Ffar2 antibody
    • FFAR2_HUMAN antibody
    • free fatty acid activated receptor 2 antibody
    • Free fatty acid receptor 2 antibody
    • G protein coupled receptor 43 antibody
    • G protein-coupled receptor 43 antibody
    • G-protein coupled receptor 43 antibody
    • GPR 43 antibody
    • GPR43 antibody
    see all

图片

  • ab124272, at 5 µg/ml, staining GPCR GPR43 in formalin fixed, embedded Human tonsil tissue by Immunohistochemistry.
  • ab124272, at a 1/100 dilution, staining GPCR GPR43 in COS7 cells by iImmunofluorescence.
    The image on the right is treated with the synthesized peptide.

文献

ab124272 has not yet been referenced specifically in any publications.

客户评价及客户问答

The homology of this immunogen sequence to mouse is not good, only about 60%. It is possible yet unlikely that ab124272 will cross react with mouse protein.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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