Anti-GPCR GPR17抗体(ab106781)

概述

  • 产品名称Anti-GPCR GPR17抗体
    参阅全部 GPCR GPR17 一抗
  • 描述
    山羊多克隆抗体to GPCR GPR17
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide:

    C-EGKTNESSLSAKSE

    , corresponding to C terminal amino acids 353-366 of Human GPCR GPR17 (NP_005282.1).

  • 阳性对照
    • Human cerebellum lysate; Mouse and Rat brain lysates

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab106781 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 45 kDa (predicted molecular weight: 41 kDa).

靶标

  • 功能Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.
  • 组织特异性Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.
  • 序列相似性Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp686M18273 antibody
    • G protein coupled receptor 17 antibody
    • G-protein coupled receptor 17 antibody
    • GPR 17 antibody
    • Gpr17 antibody
    • GPR17_HUMAN antibody
    • P2Y like receptor antibody
    • P2Y-like receptor antibody
    • Probable P2Y purinoceptor GPR 17 antibody
    • Probable P2Y purinoceptor GPR17 antibody
    • R12 antibody
    • UDP/CysLT receptor antibody
    • Uracil nucleotide/cysteinyl leukotriene receptor antibody
    see all

Anti-GPCR GPR17 antibody 图像

  • Anti-GPCR GPR17 antibody (ab106781) at 0.3 µg/ml + Rat brain lysates at 35 µg

    Predicted band size : 41 kDa
  • Anti-GPCR GPR17 antibody (ab106781) at 0.1 µg/ml + Human brain (cerebellum) lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 41 kDa
    Observed band size : 45 kDa (why is the actual band size different from the predicted?)


    Exposure time : 1 hour

Anti-GPCR GPR17 antibody (ab106781)参考文献

ab106781 has not yet been referenced specifically in any publications.

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