GPCR GPR15肽(ab6101)

概述

  • 产品名称
    GPCR GPR15肽

描述

  • 性质
    Synthetic

相关产品

技术指标

Our Abpromise guarantee covers the use of ab6101 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

    Blocking

  • 形式
    Liquid
  • 补充说明
    Stable for one year.


    Human immunodeficiency virus (HIV) and related viruses require co-receptors to infect target cells. Some G protein coupled receptors, including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV co-receptors. The genes encoding human and monkey GPR15/BOB (for G protein-coupled receptor 15 and brother of Bonzo, respectively) were recently cloned. This novel G protein coupled receptor serves as co-receptor for simian immunodeficiency virus (SIV), and for strains of HIV-2 and M-tropic HIV-1. The ligand for GPR15 has not been identified yet.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

常规信息

  • 别名
    • BOB
    • Brother of Bonzo
    • G protein coupled receptor 15
    • G protein coupled receptor GPR15
    • G-protein coupled receptor 15
    • GPR15
    • GPR15_HUMAN
    see all
  • 功能
    Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection.
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family.
  • 细胞定位
    Cell membrane.
  • Information by UniProt

文献

ab6101 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for your enquiry regarding ab6101 GPR15 (N-term) peptide. As far as I we are aware the only tested application for this antibody is blocking. All other information we have available pertaining this antibody is accesible on the online datashee...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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